How Does Advandamet Work?
Advandamet comes in the form of tablets and contains two active ingredients, rosiglitazone maleate and metformin hydrochloride. These are both medicines that are used to help control blood sugar levels in people with type 2 or non-insulin dependent diabetes (NIDDM).
Patients with diabetes mellitus have a deficiency or absence of insulin. Insulin is the main hormone responsible for the control of sugar in the blood. In type 2 diabetes the pancreas does not produce sufficient insulin and the cells of the body are resistant to the low levels of insulin circulating in the blood. Insulin would normally make the cells remove sugar from the blood, hence in type 2 diabetes blood sugar levels can rise too high.
Metformin hydrochloride is a type of antidiabetic medicine known as a biguanide. It works in a number of ways to decrease the amount of sugar in the blood. It reduces the amount of sugar produced by cells in the liver. Then it increases the sensitivity of muscle cells to insulin. This enables these cells to remove sugar from the blood more effectively. Lastly, it also delays absorption of sugar from the intestines into the bloodstream after eating.
Rosiglitazone maleate is a type of antidiabetic medicine known as a thiazolidinedione or glitazone. Its main fucnction is to help control blood sugar levels by increasing the sensitivity of the liver, fat and muscle cells to insulin. This enables these cells to remove sugar from the blood more effectively. Rosiglitazone also preserves the functioning of the cells in the pancreas (beta cells) that produce insulin.
posted by blogger1215 @ 09:22
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